产品详情
简单介绍：
Anti-CREB3L3抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-CREB3L3抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-CREB3L3
Cat. Number:
Anti-CREB3L3抗体KL-11239R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulumAnti-CREB3L3抗体 (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.
Also known as:
cAMP responsive Anti-CREB3L3抗体element binding protein 3 like 3; cAMP responsive element-binding protein 3 like protein 3; CREB H; CREB/ATF family transcription factor; CREBH; Cyclic AMP responsive element binding protein 3 like protein 3; cAMP-responsive element-binding protein 3-like protein 3; HYST1481; MGC126553; MGC126557; Transcription factor CREB H; CR3L3_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human CREB-H.
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Predicted Molecular Anti-CREB3L3抗体Weight: 49kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other Anti-CREB3L3抗体applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other Anti-CREB3L3抗体applications.
Optimal working dilutions must be determined by the end user.
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