产品详情
简单介绍：
Anti-Desmoplakin I+II抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Desmoplakin I+II抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Desmoplakin I+II
Cat. Number:
Anti-Desmoplakin I+II抗体KL-12953R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Desmosomes are intercellular junctions that form tight links between adjacent cells. Desmoplakin is an obligate Anti-Desmoplakin I+II抗体component of functional desmosomes that attaches intermediate filaments to desmosomal plaques. It is involved in the organization of desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains. The N-terminus of desmoplakin is essential for localisation to the desmosome and interaction with plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds to intermediate filaments. The central region of desmoplakin comprises a coiled-coil rod domain that mediates homodimerisation. There are two isoforms of desmoplakin - desmoplakin I, which is an obligate component of all desmosomes, and desmoplakin II, which is predominantly expressed in tissues and cells of stratified origin. Mutations in the gene encoding desmoplakin result in a number of cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
Also known as:
250/210 kDa paraneoplasticAnti-Desmoplakin I+II抗体 pemphigus antigen; Desmoplakin (DPI DPII); Desmoplakin; Desmoplakin I; Desmoplakin II; DESP_HUMAN; DP; DP I; DP II; DPI; DPII; DSP; KPPS2; PPKS 2; PPKS2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Cow, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human DP-I.
●
Predicted Molecular Weight: 331kDa.
Storage:
Shipped at 4℃, Store at -20℃ Anti-Desmoplakin I+II抗体(Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutionsAnti-Desmoplakin I+II抗体 must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutionsAnti-Desmoplakin I+II抗体 must be determined by the end user.
kl878Hu01 凝血因子Ⅷ(F8)多克隆抗体 Polyclonal Antibody to Coagulation Factor VIII (F8)
kl878Mu01 凝血因子Ⅷ(F8)多克隆抗体 Polyclonal Antibody to Coagulation Factor VIII (F8)
kl879Hu01 载脂蛋白F(APOF)多克隆抗体 Polyclonal Antibody to Apolipoprotein F (APOF)
kl879Ra01 载脂蛋白F(APOF)多克隆抗体 Polyclonal Antibody to Apolipoprotein F (APOF)
kl880Hu01 周期素依赖性激酶7(CDK7)多克隆抗体 Polyclonal Antibody to Cyclin Dependent Kinase 7 (CDK7)
kl882Hu01 成纤维细胞生长因子10(FGF10)多克隆抗体 Polyclonal Antibody to Fibroblast Growth Factor 10 (FGF10)
kl882Ra01 成纤维细胞生长因子10(FGF10)多克隆抗体 Polyclonal Antibody to Fibroblast Growth Factor 10 (FGF10)
kl884Mu01 受磷蛋白(PLN)多克隆抗体 Polyclonal Antibody to Phospholamban (PLN)
kl886Hu01 血管紧张素转化酶2(ACE2)多克隆抗体 Polyclonal Antibody to Angiotensin I Converting Enzyme 2 (ACE2)
kl886Ra01 血管紧张素转化酶2(ACE2)多克隆抗体 Polyclonal Antibody to Angiotensin I Converting Enzyme 2 (ACE2)
kl888Hu01 周期素依赖性激酶1(CDK1)多克隆抗体 Polyclonal Antibody to Cyclin Dependent Kinase 1 (CDK1)
kl889Hu01 周期素依赖性激酶2(CDK2)多克隆抗体 Polyclonal Antibody to Cyclin Dependent Kinase 2 (CDK2)
kl890Hu01 载脂蛋白C3(APOC3)多克隆抗体 Polyclonal Antibody to Apolipoprotein C3 (APOC3)
kl890Mu01 载脂蛋白C3(APOC3)多克隆抗体 Polyclonal Antibody to Apolipoprotein C3 (APOC3)
kl890Ra01 载脂蛋白C3(APOC3)多克隆抗体 Polyclonal Antibody to Apolipoprotein C3 (APOC3)
kl893Bo01 血管内皮生长因子受体3(VEGFR3)多克隆抗体 Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 3 (VEGFR3)
