产品详情
简单介绍：
Anti-DENND5B抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-DENND5B抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-DENND5B
Cat. Number:
Anti-DENND5B抗体KL-14275R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
DENND5B is a 1,274 amino acid single-pass membrane protein containing a dDENN domain, a DENN domain, a PLAT domain, Anti-DENND5B抗体two RUN domains and an uDENN domain. Existing as four alternatively spliced isoforms, DENND5B is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
Also known as:
DENN domain containing Anti-DENND5B抗体protein 5B; DENN MADD domain containing 5B; Dennd5b; DEN5B_HUMAN； Rab6IP1 like protein.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Chicken, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human DENND5B.
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Predicted Molecular Weight: 145kDa.
Storage:
Shipped at 4℃, Store at -20℃Anti-DENND5B抗体 (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must Anti-DENND5B抗体be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must Anti-DENND5B抗体be determined by the end user.
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