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  • 产品名称：Anti-Phospho-Gab1 (Tyr659)抗体

  • 产品型号：磷酸化接头蛋白Gab 1抗体
  • 产品厂商：KALANG
  • 产品文档：
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简单介绍：
Anti-Phospho-Gab1 (Tyr659)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phospho-Gab1 (Tyr659)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit  Anti-Phospho-Gab1 (Tyr659)
Cat. Number:
Anti-Phospho-Gab1 (Tyr659)抗体KL-3166R
Quantity size:
0.1ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Gab1 is a 115 kDa multiple docking protein that plays an essential role in cellular growth, transformation and apoptosis. Anti-Phospho-Gab1 (Tyr659)抗体Gab1 can be phosphorylated by multiple receptor tyrosine kinase (RTKs), including: insulin receptor (IR), platelet derived growth factor receptor beta] (PDGFRbeta]), hepatocyte growth factor/scatter factor receptor (HGFR/SFR or c Met), and epidermal growth factor receptor (EGF), as well as in response to cell cell adhesion. Gab1 is tyrosine phosphorylated on at least 16 sites, some of which serve as binding sites for phosphoatidylinositol 3 kinase (PI3K), Grb2, PLC gamma 1, Nck, and SHP2. Phosphorylation of Gab1 on tyrosines 627 and 659 is critical for its binding to SHP2, and for activation of the ERK/MAPK pathway in response to EGF.
Also known as:
GAB1 (phospho Y659); p-GAB1Anti-Phospho-Gab1 (Tyr659)抗体 (phospho Y659); GRB 2 associated binder 1; GRB 2 associated binding protein 1; GRB2 associated binding protein 1 isoform a; GRB2 associated binding protein 1 isoform bl; Gab 1; Gab1; GAB1_HUMAN; GRB2 associated binder 1; GRB2 associated binding protein 1 isoform b; GRB2-associated binder 1; GRB2-associated-binding protein 1; Growth factor receptor bound protein 2-associated protein 1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Anti-Phospho-Gab1 (Tyr659)抗体Chicken, Dog, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.
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Predicted Molecular Weight: 76kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. Anti-Phospho-Gab1 (Tyr659)抗体
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