产品详情
简单介绍：
Anti-GABPB2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-GABPB2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-GABPB2
Cat. Number:
Anti-GABPB2抗体KL-13262R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, GABP beta. GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABPAnti-GABPB2抗体 beta is expressed in both the cytoplasm and the nucleus, whereas GABP alpha is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo . The GABP alpha beta tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
Also known as:
MGC29891; BABPB2; E4TF1; Anti-GABPB2抗体E4TF1-47; E4TF1-53; E4TF1B; GA binding protein transcription factor beta subunit 1 transcript variant gamma 2; GA binding protein transcription factor, beta subunit 1; GA binding protein transcription factor, beta subunit 2; GA-binding protein subunit beta-1; GABP subunit beta-1; GABP subunit beta-2; GABP1_HUMAN; GABPB; GABPB-1; GABPB-2; GABPB1; GABPB2; NRF2B1; NRF2B2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Cow, Horse, .
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Immunogen: KLH conjugated synthetic peptide derived from human GABPB2/G.
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Predicted Molecular Weight: 42kDa.Anti-GABPB2抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-GABPB2抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-GABPB2抗体
Optimal working dilutions must be determined by the end user.
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