产品详情
简单介绍：
Anti-GJA8抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-GJA8抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-GJA8
Cat. Number:
Anti-GJA8抗体KL-13364R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The connexin family of proteins form hexameric complexes called “connexons” that facilitate movement of low molecular weight proteins between cells via gap junctions (1). Connexin proteins share a common topology of Anti-GJA8抗体4 transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop, and cytoplasmic N- and C-termini (2). Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions (2). Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another (2). Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected (3, 2). For instance, deletion of the gene encoding connexin 50, normally expressed in the lens, produces cataracts, though not as severe as with deletion of connexin 46 (4).
Also known as:
CAE; CAE1; cataract, zonular pulverulent 1 Anti-GJA8抗体(FY-linked); Connexin 50; Connexin50; Connexin-50; Cx50; CXA8_HUMAN; Gap junction alpha 8 protein; Gap junction alpha-8 protein; Gap junction membrane channel protein alpha 8 (connexin 50); gap junction protein, alpha 8, 50kD; Gja8; Lens fiber protein MP70.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human GJA8/Con.
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Predicted Molecular Weight: 48kDa.Anti-GJA8抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-GJA8抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-GJA8抗体
Optimal working dilutions must be determined by the end user.
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