产品详情
简单介绍：
Anti-Guanylate Cyclase抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Guanylate Cyclase抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-Guanylate Cyclase
Cat. Number:
Anti-Guanylate Cyclase抗体KL-16371R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor Anti-Guanylate Cyclase抗体form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one ?subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver
Also known as:
GC SB2; GCS BETA 2; GTP pyrophosphateAnti-Guanylate Cyclase抗体 lyase; Guanylate cyclase 1 soluble beta 2; GCYA2_HUMAN; Guanylate cyclase soluble beta 2; Guanylate cyclase soluble beta 2 chain; Guanylate cyclase soluble subunit beta 2; Gucy1b2; Gucy1b2a; Gucy1b2b; SGC; Soluble guanylate cyclase beta 2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Guanylat.
●
Predicted Molecular Weight: 82kDa.Anti-Guanylate Cyclase抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Anti-Guanylate Cyclase抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl709Hu01 杀伤细胞**球蛋白样受体2DL3(KIR2DL3)多克隆抗体 Polyclonal Antibody to Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3)
kl712Hu01 杀伤细胞**球蛋白样受体2DS2(KIR2DS2)多克隆抗体 Polyclonal Antibody to Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2)
kl992Hu01 杀伤细胞**球蛋白样受体3DL2(KIR3DL2)多克隆抗体 Polyclonal Antibody to Killer Cell Immunoglobulin Like Receptor 3DL2 (KIR3DL2)
kl714Hu01 杀伤细胞**球蛋白样受体3DL3(KIR3DL3)多克隆抗体 Polyclonal Antibody to Killer Cell Immunoglobulin Like Receptor 3DL3 (KIR3DL3)
kl348Mu01 组织蛋白酶A(CTSA)多克隆抗体 Polyclonal Antibody to Cathepsin A (CTSA)
kl635Mu01 CUB带状疮疹透明区样域蛋白1(CUZD1)多克隆抗体 Polyclonal Antibody to CUB And Zona Pellucida Like Domains Protein 1 (CUZD1)
kl103Mu01 丝聚蛋白(FLG)多克隆抗体 Polyclonal Antibody to Filaggrin (FLG)
kl911Mu01 肝细胞生长因子激活因子(HGFAC)多克隆抗体 Polyclonal Antibody to Heklocyte Growth Factor Activator (HGFAC)
kl352Mu01 己糖激酶2(HK2)多克隆抗体 Polyclonal Antibody to Hexokinase 2 (HK2)
kl644Mu01 白介素17受体A(IL17RA)多克隆抗体 Polyclonal Antibody to Interleukin 17 Receptor A (IL17RA)
kl691Mu01 激肽释放酶6(KLK6)多克隆抗体 Polyclonal Antibody to Kallikrein 6 (KLK6)
kl690Mu01 激肽释放酶8(KLK8)多克隆抗体 Polyclonal Antibody to Kallikrein 8 (KLK8)
kl780Mu02 乳铁传递蛋白(LTF)多克隆抗体 Polyclonal Antibody to Lactoferrin (LTF)
kl780Mu03 乳铁传递蛋白(LTF)多克隆抗体 Polyclonal Antibody to Lactoferrin (LTF)
kl290Mu01 V-Myc骨髓细胞瘤病毒癌基因同源物(MYC)多克隆抗体 Polyclonal Antibody to V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC)
