产品详情
简单介绍：
Anti-phospho-HDAC1 (Ser423+Ser421)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-HDAC1 (Ser423+Ser421)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-phospho-HDAC1 (Ser423+Ser421)
Cat. Number:
Anti-phospho-HDAC1 (Ser423+Ser421)抗体KL-5388R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an importantAnti-phospho-HDAC1 (Ser423+Ser421)抗体 role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs). Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1). Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases. Belongs to the histone deacetylase family. Type 1.
Also known as:
HDAC1 (phospho S421 + S423); Anti-phospho-HDAC1 (Ser423+Ser421)抗体p-HDAC1 (phospho S421 + S423); dHDAC1 (phospho S421 + S423); p-dHDAC1 (phospho S421 + S423); DKFZp686H12203; GON 10; HD 1; HD1; HDAC 1; hdac1: histone deacetylase 1; Histone deacetylase 1 (HD1); Histone deacetylase 1; RPD3 (reduced potassium dependency yeast homolog) like 1; RPD3 (reduced potassium dependency); RPD3; RPD3L1; HDAC2_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.
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Predicted Molecular Weight: 55kDa.Anti-phospho-HDAC1 (Ser423+Ser421)抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-HDAC1 (Ser423+Ser421)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-HDAC1 (Ser423+Ser421)抗体
Optimal working dilutions must be determined by the end user.
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