产品详情
简单介绍：
Anti-HPV16 L2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-HPV16 L2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-HPV16 L2
Cat. Number:
Anti-HPV16 L2抗体KL-8547R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Human papillomaviruses, particularly type 16 (designated HPV16), infect the genital tract and may lead to cervical cancer. Protection against HPV16 is thought to be provided by neutralizing antibodies directed to the major Anti-HPV16 L2抗体caspid protein L1 of HPV16. HPV16 L1 forms the pentameric assembly unit of the viral shell, and the binding of HPV16 L1 to the cell surface without the involvement of minor capsid protein L2 is believed to be the first step of HPV16 infection. The L1-binding domain located near the C-terminus of L2 binds L1 prior to completion of capsid assembly and is required for efficient encapsidation of the viral genome. In addition, the C-terminus of L1 is necessary for both DNA binding and DNA packaging. Expression of the late gene L1 is restricted to the upper layers of the infected epithelium. HPV16 L1 is able to package unrelated plasmid DNA in vitro and deliver the foreign DNA to eukaryotic cells with the subsequent expression of the encoded gene. L1 shows a diffuse nuclear distribution whereas L2 is localized to punctate nuclear regions identified as promonocytic leukemia protein oncogenic domains (PODs). Coexpression of L1 and L2 induces a relocalization of L1 into the PODs.
Also known as:
HPV16 L2; HPV16-L2; HPV-16; HPV-16 Anti-HPV16 L2抗体capsid; HPV16 capsid protein; HPV16 major capsid protein L2; Human papillomavirus type 16 L2; Human papillomavirus type 16 major capsid protein L2; Major capsid L2 protein; Major capsid protein; Major capsid protein L2; VL2_HPV16.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: HPV16.
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Immunogen: KLH conjugated synthetic peptide derived from HPV16 L2.
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Predicted Molecular Weight: 52kDa.Anti-HPV16 L2抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
Not yet tested in other applications. Anti-HPV16 L2抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HPV16 L2抗体
Optimal working dilutions must be determined by the end user.
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