产品详情
简单介绍：
Anti-HLA-DRB4抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-HLA-DRB4抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-HLA-DRB4
Cat. Number:
Anti-HLA-DRB4抗体KL-18041R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in Anti-HLA-DRB4抗体antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB4 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008]
Also known as:
DR 4; DR beta 4 chain; DR4; DRB1Anti-HLA-DRB4抗体 transplantation antigen; DRB4; DRB4_HUMAN; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DR beta 4 chain; HLA-DRB4; Human leucocyte antigen DRB4; Leukocyte antigen; Major histocompatibility complex class II DR beta 4; MHC class II antigen DRB4; MHC class II antigen HLA DR beta; MHC class2 antigen; MHC HLA DR-beta chain.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Dog, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human HLA-DRB4.
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Predicted Molecular Weight: 27kDa.Anti-HLA-DRB4抗体
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HLA-DRB4抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-HLA-DRB4抗体
Optimal working dilutions must be determined by the end user.
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