产品详情
简单介绍：
Anti-LAT2抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-LAT2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-LAT2
Cat. Number:
Anti-LAT2抗体KL-17109R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
L-amino acid transporter protein-2 (LAT2), a non-glycosylated membrane protein, complexes with CD98 to contribute to readsorption of neutral amino acids in renal epithelia and blood-tissue barriers. The gene encoding LAT2 is expressed primarily in the kidney, but also to a lesser extent in placenta, brain, liver, spleen, skeletal muscle, Anti-LAT2抗体heart, small intestine, and lung. Transfection with the antisense sequence of LAT2 suggests that LAT2 expression plays a major role in net basolateral efflux of cysteine, and points to LAT2 as a candidate gene to modulate cysteine reabsorption. In addition, the CD98/LAT2 heterodimer associates with Integrin ∫1 in intestinal epithelial cells, where ligand binding to CD98 and another cell surface molecule, ICAM-1 differentially regulates LAT2 activity, suggesting a novel mechanism by which events like cell adhesion may affect amino acid transport activity.
Also known as:
hLAT2; integral membrane protein E16H; Anti-LAT2抗体L type amino acid transporter 2; L-type amino acid transporter 2; Large neutral amino acids transporter small subunit 2; LAT2_HUMAN; LPI PC1; SLC7A8; solute carrier family 7 (amino acid transporter light chain, L system), member 8; solute carrier family 7 (amino acid transporter, L type), member 8; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8; Solute carrier family 7 member 8.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Sheep, Orangutan.
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Immunogen: KLH conjugated synthetic Anti-LAT2抗体peptide derived from human LAT2.
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Predicted Molecular Weight: 61kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Anti-LAT2抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Anti-LAT2抗体
