产品详情
简单介绍:
Anti-phospho-MST1R(Tyr1353)抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-MST1R(Tyr1353)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit Anti-phospho-MST1R(Tyr1353)
Cat. Number:
Anti-phospho-MST1R(Tyr1353)抗体KL-7919R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage Anti-phospho-MST1R(Tyr1353)抗体of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. Ron expression has been documented in many normal human tissues. ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uterus.
Also known as:
p-MST1R(Tyr1353); RON (phospho Y1353); MST1R(phospho S1349); c met related tyrosine kinase; CD136 antigen; CDw136; Anti-phospho-MST1R(Tyr1353)抗体Macrophage stimulating 1 receptor; Macrophage stimulating protein receptor alpha chain; MACROPHAGE STIMULATING PROTEIN RECEPTOR; Macrophage stimulating protein receptor beta chain; MSP receptor; MST1R; p185 RON; PTK 8; ptk8; PTK8 protein tyrosine kinase 8; RON; RON protein tyrosine kinase; Stem cell derived tyrosine kinase.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, .
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Immunogen: KLH conjugated synthesisedAnti-phospho-MST1R(Tyr1353)抗体 phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1353 .
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Predicted Molecular Weight: 150kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-MST1R(Tyr1353)抗体
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-MST1R(Tyr1353)抗体
Optimal working dilutions must be determined by the end user.