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Anti-phospho-LRP5(Thr1492)抗体 磷酸化低密度脂蛋白受体相关蛋白5抗体 KALANG

Anti-phospho-LRP5(Thr1492)抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-LRP5(Thr1492)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。

Anti-phospho-LRP5(Thr1492)抗体
产品产商:KALANG
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Anti-phospho-LRP5(Thr1492)抗体
Rabbit  Anti-phospho-LRP5(Thr1492)
Cat. Number:
Anti-phospho-LRP5(Thr1492)抗体KL-5407R
Quantity size:
0.1ml
Concentration:
1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
LRP5 is involved in the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. Defects in LRP5 are a cause of autosomal dominant and autosomal recessive familial exudative vitreoretinopathy (FEVR). Autosomal dominant FEVR is also referred to as exudative vitreoretinopathy 1Anti-phospho-LRP5(Thr1492)抗体 (EVR1); also known as Criswick-Schepens syndrome. FEVR is a disorder of the retinal vasculature characterized by an abrupt cessation of growth of peripheral capillaries, leading to an avascular peripheral retina. This may lead to compensatory retinal neovascularization, which is thought to be induced by hypoxia from the initial avascular insult. New vessels are prone to leakage and rupture causing exudates and bleeding, followed by scarring, retinal detachment and blindness. FEVR is reported to have a penetrance of 100%, but clinical features can be highly variable, even within the same family. Patients with mild forms of the disease are asymptomatic, and their only disease-related abnormality is an arc of avascular retina in the extreme temporal periphery.
Also known as:
BMND1; HBM; HGNC:6697; Anti-phospho-LRP5(Thr1492)抗体Low density lipoprotein receptor related protein 5; Low density lipoprotein receptor related protein 7; Low-density lipoprotein receptor-related protein 5; LR3; LRP-5; Lrp5; LRP5_HUMAN; LRP7; OPPG; OPS; Osteoporosis pseudoglioma syndrome; VBCH2.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, .
Immunogen: KLH conjugated Anti-phospho-LRP5(Thr1492)抗体Synthesised phosphopeptide derived from human.
Predicted Molecular Weight: 176kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. Anti-phospho-LRP5(Thr1492)抗体
Optimal working dilutions must be determined by the end user.

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